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Cellular aging is linked to structural changes in the brain

September 26, 2019

Telomeres are the protective caps of our chromosomes and play a central role in the ageing process. Shorter…
Enzyme Known for Promoting Cancer Also Protects Healthy Cells

September 4, 2019

New research from the University of Maryland and the National Institutes of Health reveals a new role for…
Runaway Mitochondria Cause Telomere Damage in Cells

August 29, 2019

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the…
Direct Oxidative Stress Damage Shortens Telomeres

May 15, 2019

The same sources thought to inflict oxidative stress on cells—pollution, diesel exhaust, smoking and obesity—also are associated with…
New Doctors’ DNA Ages 6 Times Faster Than Normal in First Year

May 15, 2019

A new study finds that the long work hours of an intern’s first year of medical residency are…
A New Biological Aging Clock: Ribosomal DNA

April 8, 2019

Chronological aging is easy to track – birthdays. Biological aging can be obvious too – graying hair, sagging skin,…
Lithium might work as an anti-aging drug, depending on your genes

December 21, 2018

There is growing evidence that lithium could be re-purposed as an anti-aging drug, and a new study from…
Two-step process leads to cell immortalization and cancer

August 18, 2017

A mutation that helps make cells immortal is critical to the development of a tumor, but new research…
Risk for bipolar disorder associated with faster ageing

July 27, 2017

The study, published in Neuropsychopharmacology, also shows that bipolar patients treated with lithium – the main medication for the illness…
Longer telomeres protect against diseases of aging: A tale of mice and men

March 28, 2017

Telomere length may explain differences in severity of genetic heart disease in humans Scientists at the Gladstone Institutes…
‘Protective’ DNA strands are shorter in adults who had more infections as infants

January 27, 2017

New research indicates that people who had more infections as babies harbor a key marker of cellular aging…
Battling aging by preserving telomeres could backfire, fueling cancer

January 13, 2017

If an anti-aging regimen that involves telomeres – part of the human chromosome – sounds too good to…
Aging and cancer: An enzyme protects chromosomes from oxidative damage

December 23, 2016

EPFL scientists have identified a protein that caps chromosomes during cell division and protect them from oxidative damage…
The Goldilocks effect in aging research

December 5, 2016

Ever since researchers connected the shortening of telomeres–the protective structures on the ends of chromosomes–to aging and disease,…
Childhood Adversity Linked with Shorter Telomeres

October 8, 2016

Major childhood psychological and social stressors, such as trouble with the police and parental substance abuse, increase the…
Childhood Adversity Linked with Shorter Telomeres

October 6, 2016

Psychological and Social Stress Associated with Health Risks in Adulthood Major childhood psychological and social stressors, such as…
Edible dormice: High food availability slows down cell aging

September 2, 2016

Hibernation has long been considered the secret behind the relatively long lifespan of the edible dormouse. However, a…
Team Identifies Strategy to Reverse the Disease Dyskeratosis Congenita

August 21, 2016

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no…
Nobel laureate, new technologies show how cancer cells protect chromosomes from decay

August 19, 2016

As the rope of a chromosomes replicates, it frays at the ends. No problem: A chromosome’s ends have…
New method detects telomere length for research into cancer, aging

June 30, 2016

UT Southwestern Medical Center cell biologists have identified a new method for determining the length of telomeres, the…
Mouse study links heart regeneration to telomere length

May 30, 2016

The ends of heart muscle cell chromosomes rapidly erode after birth, limiting the cells’ ability to proliferate and…
‘Rejuvenation factor’ Zscan4 is expressed in response to telomere shortening

March 18, 2016

Scientists from the RIKEN Center for Developmental Biology (CDB) in Kobe, Japan, have discovered that Zscan4, a protein…
New study reveals why certain organs become the weakest link in old age

January 27, 2016

Understanding why and how we age has been one of the most fundamental questions hunting scientists for decades.…
Brothers-in-arms: How P53 and telomeres work together to stave off cancer

January 17, 2016

Scientists from the Wistar Institute show that p53 has newly revealed tumor suppressor functions related to telomeres When…
A telomere structure specialized for meiosis

December 16, 2015

A University of Tokyo research group has discovered two proteins, MAJIN and TERB2, and the molecular process by…
Study links body fat, weight loss, and chromosome length in breast cancer patients

December 9, 2015

It is well documented that a healthy diet and exercise are key in cancer prevention and management, but…
Early Study Links Mothers’ Education Level to Telomere Length in Newborns

December 7, 2015

A small study of new mothers suggests that not having graduated from high school – possibly an indicator…
The life story of stem cells

November 10, 2015

Stem cells ensure the regeneration and maintenance of the body’s tissues. Diseases like cancer can arise if they…
New DNA insights may lead to cancer therapy

October 23, 2015

Researchers at Weill Cornell Medicine have developed a better understanding of a complex mechanism that contributes to the…
Study reveals key structure in telomerase enzyme, a target for cancer drugs

October 7, 2015

Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which…
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