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Failure of the molecular bodyguard in Parkinson’s disease


Scientists from ETH Zurich and the University of Basel’s Biozentrum have shown that chaperone proteins dynamically bind to…
‘Not all disease is the same’: study highlights protein variability in neurodegenerative diseases


A new University of Toronto study sheds light on how protein strains vary in the brains of those…
Neurodegenerative diseases may be caused by molecular transportation failures inside neurons


All neurodegenerative diseases have a common thread: the appearance of protein clumps in the brain such as amyloid-beta…
Key Alzheimer’s gene acts differently in non-Europeans

November 13, 2019

Researchers looking to uncover the mysteries of Alzheimer’s disease have revealed new insights from old variants. A gene…
Retinal imaging technology for early detection of Alzheimer’s disease

November 13, 2019

Alzheimer’s disease is the leading cause of dementia in the U.S., with approximately 5.4 million currently affected and…
‘Basket’ Trials for Dementia Aim to Bring Precision Medicine to Neurogenerative Diseases

November 12, 2019

A new type of clinical trial for dementia that aims to accelerate treatments for neurodegenerative disease by adapting…
The pathway to Parkinson’s takes a surprising twist

November 11, 2019

In neurodegenerative conditions like Parkinson’s disease, a specific group of neurons start to die one by one, causing…
Parkinson’s Disease and Your Bladder

November 8, 2019

Anne Pelletier-Cameron, M.D., often jokes to her patients that she’s a female plumber of the lower urinary tract.…
Unique case of disease resistance reveals possible Alzheimer’s treatment

November 6, 2019

Defying the odds, an individual at high risk for early-onset Alzheimer’s disease remained dementia-free for many years beyond…
Escaping Alzheimer’s

November 5, 2019

There is, in Colombia, a family with a tragic legacy of forgetfulness. “People in this large family get…
Researchers discover a way to turn Parkinson protein on itself

November 5, 2019

Researchers have found a way to create a super-inhibitor that effectively stops the development of Parkinsons by using…
Genes from ‘fossil’ virus in human DNA found to be active

November 5, 2019

Inserted in the human genome thousands of years ago, the genes can produce viral proteins without activating the…
Scientists are inching closer towards new therapies for degenerative diseases

October 31, 2019

Human body is like a huge robot, which has its movement and electronics. We are partially mechanical and…
Image credit: Leterrier, NeuroCyto Lab, INP, Marseille, France
New NIH BRAIN Initiative awards accelerate neuroscience discoveries

October 22, 2019

Scientists have been developing astounding new tools for exploring neural circuits that underlie brain function throughout the first…
Frontotemporal lobar degeneration consortium combines and continues research efforts

October 18, 2019

A new National Institutes of Health grant merges two ongoing frontotemporal lobar degeneration (FTLD) studies to form a…
NIH scientists develop test for uncommon brain diseases

October 18, 2019

National Institutes of Health scientists have developed an ultrasensitive new test to detect abnormal forms of the protein…
NIA announces major $73 million Alzheimer’s grant, Emory leads international drug discovery center

October 3, 2019

The National Institute on Aging (NIA) is awarding approximately $37 million over five years to a team of…
Scientists find potential diagnostic tool, treatment for Parkinson’s disease

September 27, 2019

In human cell cultures, countering a defect that appears to be nearly universal among patients with Parkinson’s disease…
Achilles’ heel identified in several neurodegenerative diseases

September 25, 2019

Many neurodegenerative diseases have a common feature that may make them amenable to the same treatment, investigators at…
Eisai and Meiji Announce Parkinson’s Disease Treatment Equfina Tablets (Safinamide Mesilate) Approved In Japan

September 20, 2019

Eisai Co., Ltd. and Meiji Seika Pharma Co., Ltd. has announced the manufacturing and marketing approval in Japan…
Research suggests how environmental toxin produced by algae may lead to ALS

September 17, 2019

Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to…
Summit to tackle tricky problems of aging and dementia

September 17, 2019

Human life expectancy has more than doubled over the last century, and this sudden leap in longevity is…
Calcium channel blockers may be effective in treating memory loss associated with Alzheimer’s

September 12, 2019

Alzheimer’s disease (AD) is the most common cause of dementia but the changes in brain cell function underlying…
New drug may protect against memory loss in Alzheimer’s disease

September 10, 2019

A new drug discovered through a research collaboration between the University at Buffalo and Tetra Therapeutics may protect…
Parkinson’s disease may originate in the intestines

September 4, 2019

In 2003, a German neuropathologist proposed that Parkinson’s disease, which attacks the brain, actually might originate from the…
Electronic records pin broad set of health risks on genetic premutation

August 26, 2019

It was long believed the FMR1 premutation — an excessive number of trinucleotide repeats in the FMR1 gene…
Scientists uncover how cells kill themselves for the benefit of the organism

August 23, 2019

You are just billions of different cells interacting between themselves in order to maintain this big beautiful organism…
Scientists identify faulty molecular recycling as potential driver of Alzheimer’s disease

August 19, 2019

When a muscle or lung cell gets damaged beyond repair, self-destruct enzymes, known as caspases, spring into action,…
Characterizing tau aggregates in neurodegenerative diseases

August 16, 2019

The microtubule-binding protein tau in neurons of the central nervous system can misfold into filamentous aggregates under certain…
Genes linked to Alzheimer’s risk, resilience ID’d

August 16, 2019

An international team of researchers led by scientists at Washington University School of Medicine in St. Louis has…
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