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New NIH BRAIN Initiative awards accelerate neuroscience discoveries

Today

Scientists have been developing astounding new tools for exploring neural circuits that underlie brain function throughout the first…
Frontotemporal lobar degeneration consortium combines and continues research efforts

4 days ago

A new National Institutes of Health grant merges two ongoing frontotemporal lobar degeneration (FTLD) studies to form a…
NIH scientists develop test for uncommon brain diseases

4 days ago

National Institutes of Health scientists have developed an ultrasensitive new test to detect abnormal forms of the protein…
NIA announces major $73 million Alzheimer’s grant, Emory leads international drug discovery center

October 3, 2019

The National Institute on Aging (NIA) is awarding approximately $37 million over five years to a team of…
Scientists find potential diagnostic tool, treatment for Parkinson’s disease

September 27, 2019

In human cell cultures, countering a defect that appears to be nearly universal among patients with Parkinson’s disease…
Achilles’ heel identified in several neurodegenerative diseases

September 25, 2019

Many neurodegenerative diseases have a common feature that may make them amenable to the same treatment, investigators at…
Eisai and Meiji Announce Parkinson’s Disease Treatment Equfina Tablets (Safinamide Mesilate) Approved In Japan

September 20, 2019

Eisai Co., Ltd. and Meiji Seika Pharma Co., Ltd. has announced the manufacturing and marketing approval in Japan…
Research suggests how environmental toxin produced by algae may lead to ALS

September 17, 2019

Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to…
Summit to tackle tricky problems of aging and dementia

September 17, 2019

Human life expectancy has more than doubled over the last century, and this sudden leap in longevity is…
Calcium channel blockers may be effective in treating memory loss associated with Alzheimer’s

September 12, 2019

Alzheimer’s disease (AD) is the most common cause of dementia but the changes in brain cell function underlying…
New drug may protect against memory loss in Alzheimer’s disease

September 10, 2019

A new drug discovered through a research collaboration between the University at Buffalo and Tetra Therapeutics may protect…
Parkinson’s disease may originate in the intestines

September 4, 2019

In 2003, a German neuropathologist proposed that Parkinson’s disease, which attacks the brain, actually might originate from the…
Electronic records pin broad set of health risks on genetic premutation

August 26, 2019

It was long believed the FMR1 premutation — an excessive number of trinucleotide repeats in the FMR1 gene…
Scientists uncover how cells kill themselves for the benefit of the organism

August 23, 2019

You are just billions of different cells interacting between themselves in order to maintain this big beautiful organism…
Scientists identify faulty molecular recycling as potential driver of Alzheimer’s disease

August 19, 2019

When a muscle or lung cell gets damaged beyond repair, self-destruct enzymes, known as caspases, spring into action,…
Characterizing tau aggregates in neurodegenerative diseases

August 16, 2019

The microtubule-binding protein tau in neurons of the central nervous system can misfold into filamentous aggregates under certain…
Genes linked to Alzheimer’s risk, resilience ID’d

August 16, 2019

An international team of researchers led by scientists at Washington University School of Medicine in St. Louis has…
Experimental treatment slows prion disease, extends life of mice

August 5, 2019

Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by…
The empty octopus in the cell

August 2, 2019

A fundamental research study on microRNAs, tiny molecules that help control gene activity inside plants and animals, has…
Team IDs Spoken Words and Phrases in Real Time from Brain’s Speech Signals

August 2, 2019

UC San Francisco scientists recently showed that brain activity recorded as research participants spoke could be used to create…
Cleveland researchers recruiting for Alzheimer’s disease clinical trial

July 29, 2019

Case Western Reserve University School of Medicine and University Hospitals (UH) Cleveland Medical Center have enrolled their first…
Taking out the Protein Garbage Becomes More Difficult as Neurons Age

July 25, 2019

Cells dispose of harmful “trash” through autophagy, a normal and necessary process in which aggregated proteins and dysfunctional…
Beyond finding a gene

July 23, 2019

Families living with extremely rare neurodegenerative diseases finally received an answer to the cause of their illnesses, thanks…
Multiple Sclerosis Attacks Brain’s ‘Projection Neurons’

July 18, 2019

Brain damage associated with multiple sclerosis (MS) specifically targets a common class of brain cells called projection neurons,…
Healthy blood vessels may be the answer to Alzheimer’s prevention

July 16, 2019

USC research into Alzheimer’s — which will be on display at the upcoming Alzheimer’s Association International Conference —…
Infection-fighting protein senses protein misfolding in non-infected cells

July 15, 2019

Researchers at the University of Toronto have uncovered an immune mechanism where host cells combat bacterial infection –…
Scientists identify interactions that stabilize a protein associated with neurodegeneration

July 3, 2019

Understanding the normal molecular interactions could aid in the development of therapeutics to prevent the formation of clumps…
Moments of Clarity, Glimmers of Hope

July 2, 2019

It happens unexpectedly: a person long thought lost to the ravages of dementia, unable to recall the events…
Protein-linked sugars are crucial for the uptake of proteins linked to Parkinson’s disease

July 1, 2019

Parkinson’s disease, a neurodegenerative disorder that affects more than 6 million people worldwide, is caused by the buildup…
A new drug target for chemically induced Parkinson’s disease

June 25, 2019

More than three decades ago, scientists discovered that a chemical found in a synthetic opioid, MPTP, induced the…
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