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Time-resolved serial synchrotron crystallography captures all key states of catalysis while revealing allosteric transmission pathway between the two subunits of the enzyme. Credit: MPG
‘Breathing’ enzymes in fast motion

September 24, 2019

Researchers from the Department of Atomically Resolved Dynamics of the Max Planck Institute for the Structure and Dynamics…
Discovery of periodic tables for molecules

September 9, 2019

Scientists at Tokyo Institute of Technology (Tokyo Tech) develop tables similar to the periodic table of elements but…
Molecule discovered that regulates the development of cancer in a variety of human tumors

September 4, 2019

Sonia Guil, leader of the Regulatory and Chromatin RNA group of Josep Carreras Leukemia Research Institute, and Lourdes…
Researchers reverse engineer the ‘fireworks of life’

August 8, 2019

Imagine standing in a lumberyard and being asked to build a house — without blueprints or instructions of…
Molecular Sensor Scouts DNA Damage and Supervises Repair

July 23, 2019

In the time it takes you to read this sentence, every cell in your body suffers some form…
Unmasking mutant cancer cells

July 18, 2019

As cancer cells progress, they accumulate hundreds and even thousands of genetic and epigenetic changes, resulting in protein…
Artificial cells can deliver molecules better than the real thing

July 17, 2019

From pills to vaccines, ways to deliver drugs into the body have been constantly evolving since the early…
New CRISPR platform expands RNA editing capabilities

July 15, 2019

CRISPR-based tools have revolutionized our ability to target disease-linked genetic mutations. CRISPR technology comprises a growing family of tools that…
Researchers develop fast, efficient way to build amino acid chains

July 10, 2019

Scientists often build new protein molecules by stringing groups of amino acids together. These amino acid chains, called…
Molecular thumb drives: Researchers store digital images in metabolite molecules

July 4, 2019

DNA molecules are well known as carriers of huge amounts of biological information, and there is growing interest…
Docking calculations can accelerate drug discovery by predicting the bound poses of ligands for a targeted protein. However, it is not clear which docking methods work best. The Continuous Evaluation of Ligand Protein Predictions (CELPP) takes advantage of the continuous stream of data in the Protein Data Bank (PDB) to host a weekly public challenge designed to address this question, and ultimately, accelerate the creation of new and safer medications. Image by Lorenzo Casalino, UC San Diego
UC San Diego Chemists Take Aim at Drug Predictions

June 30, 2019

As many American consumers know, “pharma” means the big business of drug therapy. According to the U.S. National…
“Nanoemulsion” gels offer new way to deliver drugs through the skin

June 25, 2019

MIT chemical engineers have devised a new way to create very tiny droplets of one liquid suspended within…
Chemists discover structure of glucagon fibrils

June 25, 2019

Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps their cells…
Pulsating Cells

May 30, 2019

Cell membranes are the key regulating factor for biological processes at the tissue-scale. The application of an electric…
Bacteria Change Behavior To Tackle Tiny Obstacle Course

May 22, 2019

It’s not exactly the set of TV’s “American Ninja Warrior,” but a tiny obstacle course for bacteria has…
Researchers Unravel Mechanisms that Control Cell Size

May 22, 2019

Working with bacteria, a multidisciplinary team at the University of California San Diego has provided new insight into…
Big energy savings for tiny machines

May 21, 2019

Inside all of us are trillions of tiny molecular nanomachines that perform a variety of tasks necessary to…
Jawless fish take a bite out of the blood-brain barrier

May 16, 2019

A jawless parasitic fish could help lead the way to more effective treatments for multiple brain ailments, including…
Research explains nature of key plant-fungus interfaces

March 6, 2019

For millions of years, plants and fungi have exchanged crucial nutrients such as phosphate and fatty acids. These…
Learning the loops

February 28, 2019

Researchers have uncovered the structural movements of a common class of molecules. The results will provide new methods…
Predicting sequence from structure

February 20, 2019

One way to probe intricate biological systems is to block their components from interacting and see what happens.…
Working proteins make good use of frustration

February 15, 2019

Proteins fold according to a script written in the pattern of their amino acids. But to function properly,…
A better way to measure cell survival

February 6, 2019

Measuring the toxic effects of chemical compounds on different types of cells is critical for developing cancer drugs,…
Molecular Analysis of Anchiornis Feather Gives Clues to Origin of Flight

January 29, 2019

An international team of researchers has performed molecular analysis on fossil feathers from a small, feathered dinosaur from…
Scientists discover natural fitness watch in fishes that records their activity levels

January 21, 2019

An international research team including scientists from the University of Southampton have shown for the first time that…
Researchers develop comprehensive new way to predict breast cancer risk

January 15, 2019

Scientists have created the most comprehensive method yet to predict a woman’s risk of breast cancer, according to…
Researchers gain control over soft-molecule synthesis

January 15, 2019

By gaining control over shape, size and composition during synthetic molecule assembly, researchers can begin to probe how…
Major Study Sheds Light on Plant Growth

January 11, 2019

How does your garden grow? A paper published in the journal Nature gives scientists a deeper understanding of that very…
Researchers unravel mystery of how, when DNA replicates

December 28, 2018

A team of Florida State University researchers has unlocked a decades-old mystery about how a critical cellular process…
Molecule predicts patient’s ability to survive melanoma

December 21, 2018

Doctors may be able to assess the survival rates of melanoma patients following the discovery of a molecule…
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