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Mitochondrial Mixing Mechanism Critical for Sperm Production in Mice

November 19, 2019

Mitochondria, often thought of as the powerhouses of cells, are just one part of a larger living thing,…
Oxygen deficiency rewires mitochondria

November 11, 2019

Mitochondria burn oxygen and provide energy for the body. Cells lacking oxygen or nutrients have to change their…
Mitochondria studies critical to search for heart failure cure

October 2, 2019

The power of mitochondrial science has the potential to unlock new solutions for heart failure, according to a…
Study points to new drug target in fight against cancer

September 19, 2019

Researchers have identified a potential new drug target in the fight against cancer. In a study in the Proceedings of…
Tiny thermometer measures how mitochondria heat up the cell by unleashing proton energy

September 2, 2019

Armed with a tiny new thermometer probe that can quickly measure temperature inside of a cell, University of…
Runaway Mitochondria Cause Telomere Damage in Cells

August 29, 2019

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the…
New Clues on Stem Cell Transplant Rejection Revealed in Study

August 22, 2019

In 2006, scientists discovered a way to “reprogram” mature cells – adult skin cells, for example – into…
A mitochondrial gene that causes cytoplasmic male infertility was deleted using a mitoTALENs technique. Infertile rice (right) stands straight, but fertile rice (left) bends under the weight of heavy seeds. Image credit: Tomohiko Kazama, CC-BY
Researchers can finally modify plant mitochondrial DNA

July 9, 2019

Researchers in Japan have edited plant mitochondrial DNA for the first time, which could lead to a more…
Cancer cell’s “self eating” tactic may be its weakness

July 2, 2019

Cancer cells use a bizarre strategy to reproduce in a tumor’s low-energy environment; they mutilate their own mitochondria!…
Study: Phenols in cocoa bean shells may reverse obesity-related problems in mouse cells

June 30, 2019

Scientists may have discovered more reasons to love chocolate. A new study by researchers at the University of…
Any which way: Flies go all-in to overcome defect, reach adulthood

June 14, 2019

New research from the University of Nebraska-Lincoln has revealed how fruit fly larvae with a seemingly fatal flaw…
Interplay between mitochondria and the nucleus may have implications for changing cell’s ‘batteries’

May 29, 2019

Mitochondria, the ‘batteries’ that produce our energy, interact with the cell’s nucleus in subtle ways previously unseen in…
A link between mitochondrial damage and osteoporosis

May 13, 2019

Some risk factors for osteoporosis such as being older and female or having a family history of the…
Simple sea anemones not so simple after all

April 25, 2019

The tube-dwelling anemone is an ancient sea creature that resembles a prehistoric flower. The animals live slow, long…
In Mice, Eliminating Damaged Mitochondria Alleviates Chronic Inflammatory Disease

April 17, 2019

Inflammation is a balanced physiological response – the body needs it to eliminate invasive organisms and foreign irritants,…
Better together: Mitochondrial fusion supports cell division

February 28, 2019

Mitochondria are the powerhouses of the cell. And for mitochondria, much like for double-header engines stacked together in…
Differences in geographic origin of a person’s mitochondrial and nuclear genomes due to admixture can affect function of mitochondria, energy-generating organelles located inside cells that have their own separate genome. A new study reveals that mitochondrial DNA (mtDNA) copy number decreases with increasing “mito-nuclear” dissimilarity in geographic origins of the mitochondrial and nuclear genomes (e.g. as the proportion of nuclear DNA from population 1 decrease). Cropped image. Image credit: Arslan Zaidi, Penn State
Differences in genes’ geographic origin influence mitochondrial function

January 15, 2019

Differences in the geographic origin of genes may affect the function of human mitochondria — energy-generating organelles inside…
How Mitochondria Deploy a Powerful Punch Against Life-Threatening Bacteria

November 19, 2018

The constant battle for dominance between disease-causing bacteria and our immune systems has led to the evolution of…
Rice University bioscientist Natasha Kirienko has won a major National Institutes of Health grant to study protective biological pathways in mitochondria. Illustration by Jeff Fitlow
Mitochondrial mechanisms focus of study

October 2, 2018

Mysteries remain in your mitochondria, but researchers led by Rice University bioscientist Natasha Kirienko plan to bring them to light. Kirienko…
Mitochondrial diseases could be treated with gene therapy, study suggests

September 25, 2018

Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions…
New species may arise from rapid mitochondrial evolution

July 13, 2018

Genetic research at Oregon State University has shed new light on how isolated populations of the same species…
Power mode for muscle cells

April 20, 2018

Muscles require a large amount of energy to function. This is provided primarily by mitochondria in cells that…
How incurable mitochondrial diseases strike previously unaffected families

January 16, 2018

Researchers have shown for the first time how children can inherit a severe – potentially fatal – mitochondrial…
Are you metabolically flexible? Your New Year’s resolutions depend on it

December 22, 2017

Looking to fend off obesity, diabetes, heart disease or other chronic ailments in the new year? Before you…
Breakthrough in understanding mitochondria

August 31, 2017

Mitochondria, which exist within human cells but have their own DNA, need many different proteins to function – but…
More functional DNA in mitochondria cures male infertility

August 7, 2017

Male infertility can be caused by mutations in the DNA of mitochondria, the powerhouses of cells. By increasing…
Researchers discover mitochondrial “circuit breaker” that protects heart from damage

April 20, 2017

A team of scientists from the National Institutes of Health has discovered biological mechanisms that appear to prevent…
How exercise — interval training in particular — helps your mitochondria stave off old age

March 8, 2017

It’s oft-repeated but true: exercise keeps you healthy. It boosts your immune system, keeps the mind sharp, helps…
Scientists slowed down aging

February 17, 2017

Synthetic compound developed in the Moscow State University slows down aging of mice with mutating A group of…
Three-Parent Babies: The Science of Replacing Mitochondrial DNA and What Remains Unknown

January 18, 2017

Mitochondrial replacement therapy (MRT) has now been used in humans to conceive a “three-parent baby” to prevent inherited…
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