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Study: Two Enzymes Control Liver Damage in NASH

February 10, 2020

As much as 12 percent of adults in the United States are living with nonalcoholic steatohepatitis (NASH), an…
Liver Fibrosis ‘Off Switch’ Discovered in Mice

January 27, 2020

Chronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar…
Death Rate Escalates for Pediatric Liver Transplant Patients in ‘Growth Failure Gap’

January 16, 2020

1 in 6 Children Loses Priority Points Due to Flawed Score System, UCSF Study Shows. Children waiting for…
3D model of human liver for better diagnosis

December 2, 2019

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of…
Regeneration mechanism discovered in mice could provide target for drugs to combat chronic liver disease

November 11, 2019

A newly-discovered molecular mechanism that allows damaged adult liver cells to regenerate could pave the way for drugs…
Cell family trees tracked to discover their role in tissue scarring and liver disease

October 17, 2019

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular…
Immune Cell Identity Crisis: What Makes a Liver Macrophage a Liver Macrophage?

October 7, 2019

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important…
Scientists triple storage time of human donor livers

September 10, 2019

Scientists have greatly extended the amount of time human livers can be stored for transplantation by modifying a…
Liver Transplant Candidates with Public Insurance Have Worse Waitlist Outcomes Than Those with Private Insurance

September 4, 2019

Patients with similar liver cancer characteristics on the waitlist for a liver transplant had significantly worse outcomes with…
One cell at a time, researchers create a blueprint of liver cells in health and disease

August 9, 2019

In every tissue throughout our bodies, various cell types are communicating and coordinating their efforts to perform vital…
Liver Damage More Common Due to Malignant Tumors than Cancer Immunotherapy Drug

August 5, 2019

Immunotherapy as a treatment for advanced solid organ tumors has rapidly evolved over the past decade, often yielding…
Liquid crystal liver

July 3, 2019

The currently used simplified model of mammalian liver tissue can only show in a limited way how liver…
What Is Hepatitis and How Is It Contracted?

June 28, 2019

There are numerous hepatitis viruses, including ones that are transmitted by water. Here’s how you can avoid getting…
It’s in the Weeds: Herbicide Linked to Human Liver Disease

May 14, 2019

Exposure to glyphosate, the primary ingredient in the popular weed killer Roundup, correlates to more severe cases of…
Movement Toward a Poop Test for Liver Cirrhosis

April 2, 2019

For the estimated 100 million U.S. adults and children living with nonalcoholic fatty liver disease (NAFLD), whether or…
Toxin Response

March 18, 2019

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved…
NIH clinical trial to track outcomes of liver transplantation from HIV-positive donors to HIV-positive recipients

February 19, 2019

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers…
Liver Transplants Double for Alcohol-Related Liver Disease

January 24, 2019

The proportion of U.S. liver transplants for alcohol-associated liver disease (ALD) has doubled in the last 15 years,…
When the body’s in overdrive, this liver hormone puts the brakes on metabolism

January 17, 2019

Researchers at the University of Michigan Life Sciences Institute have identified a hormone produced by the liver that…
Green leafy vegetables may prevent liver steatosis

December 19, 2018

A larger portion of green leafy vegetables in the diet may reduce the risk of developing liver steatosis,…
Elevated hormone flags liver problems in mice with methylmalonic acidemia

December 10, 2018

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver…
Fish can detox too – but not so well, when it comes to mercury

November 22, 2018

It takes six months to get really good at accurately gauging the age of yelloweye rockfish. Because they…
The deposition of fat into liver cells causes fundamental changes of their biology. Credit: MPI of Biochemistry/ N. Krahmer
Disorder in the liver

October 29, 2018

Chronic excessive caloric intake leads to the deposition of fat droplets in the liver. This condition, known as…
Study: Damaged liver cells undergo reprogramming to regenerate

September 27, 2018

In Greek mythology, Zeus punishes the trickster Prometheus by chaining him to a rock and sending an eagle…
Climate change increasing the prevalence of harmful parasite, warn scientists

September 3, 2018

Cattle or sheep grazing on pastures where the parasite is present can become infected with liver fluke, which…
Anti-cancer drug offers potential alternative to transplant for patients with liver failure, study finds

August 27, 2018

Acute Liver Failure occurs when a healthy liver is so seriously damaged it can no longer regrow and…
Scientists are trying to make rejected livers viable for transplantation again

August 16, 2018

The waiting list for liver transplantation is unbearably long and not getting any shorter. It is extremely taxing…
Fatty liver: Researchers uncover potential new role of long noncoding RNA

August 6, 2018

Scientists at the University of Michigan Life Sciences Institute have uncovered a potential new role for long noncoding…
Demystifying the Microbiome

August 3, 2018

Researchers studying the human microbiome—the bacteria that live in our bodies—face a chicken-and-egg problem. Say they collect data…
7 liver detox facts and why ignoring these can kill you (Infographic)

July 25, 2018

The liver is the largest organ in the human body. It circulates 30% of the blood in the…
Gut check: Metabolites shed by intestinal microbiota keep inflammation at bay

May 17, 2018

Researchers at Tufts University have elucidated a mechanism by which the “good” bacteria that reside in our gastrointestinal…
Nutmeg’s hidden power: Helping the liver

May 11, 2018

Smelling nutmeg evokes images of fall, pumpkin pie and hot apple cider. But the spice has been used…
Liver Cells Switch Identities to Grow New Tissue

May 8, 2018

By studying a rare liver disease called Alagille syndrome, scientists from UC San Francisco and Cincinnati Children’s Hospital…
Gastrointestinal Hormone Measurably Improved Symptoms of Non-Alcoholic Fatty Liver Disease

March 12, 2018

Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of…
Should uninfected patients accept hepatitis C-infected livers to reduce waiting time?

January 2, 2018

A modeling study by Massachusetts General Hospital (MGH) investigators finds that the availability of directly-acting antiviral (DAA) drugs…
McGill study finds people infected with HIV more likely to develop fatty liver

December 4, 2017

Fatty liver is among the most frequent causes of liver disease in Canada and in Western countries and…
A New Strategy for Prevention of Liver Cancer Development

November 16, 2017

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality…
Blood test spots overdose patients at risk of liver damage

November 15, 2017

People who overdose on paracetamol could be helped by a blood test that shows immediately if they are…
Fat hormone linked to progression of fatty liver disease may hold key to new treatments

November 9, 2017

The rising obesity epidemic has brought with it an army of maladies. One, in particular, is threatening to…
Common Acid Reflux Medications Promote Chronic Liver Disease

October 11, 2017

Approximately 10 percent of the general population take a proton pump inhibitor (PPI) drug to block stomach acid…
In obese adults and children, the microbiome plays key role in one of the most common and serious liver diseases

October 2, 2017

New clues to non-alcoholic fatty liver disease (NAFLD), which affects nearly all obese adults and a rising percentage…
Thirdhand Smoke Exposure Effects on Liver and Brain Found to Worsen Over Time

September 15, 2017

Researchers at the University of California, Riverside have found that thirdhand-smoke (THS) exposure has a significant effect on…
Artificial bile ducts grown in lab and transplanted into mice could help treat liver disease in children

July 4, 2017

In research the researchers grew 3D cellular structure which, once transplanted into mice, developed into normal, functioning bile…
NIH study sheds light on immune responses driving obesity-induced liver disease

June 30, 2017

New findings from mouse models reveal that the type of immune response that helps maintain healthy metabolism in…
Go Easy on the Avocado Toast: ‘Good Fat’ Can Still Be Bad for You, Research Shows

June 29, 2017

When it comes to the fat in your diet, the line between good and bad just got blurrier.…
Bioengineered livers mimic natural development

June 16, 2017

An international team of researchers from the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, Cincinnati Children’s…
Drinking more coffee could reduce liver cancer risk, suggests study

May 30, 2017

Drinking more coffee could reduce the risk of developing the most common form of primary liver cancer, according…
Intestinal fungi linked to worsening of alcoholic liver disease

May 24, 2017

A new study funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) is among the first…
Intestinal Fungi Worsen Alcoholic Liver Disease

May 23, 2017

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due…
MAGNET Study Sees Potential for MRE in Measuring Liver Fibrosis in Children

May 13, 2017

Researchers at University of California San Diego School of Medicine, with collaborators across the nation, have determined that…
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