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New genetic weapons challenge sickle cell disease

June 4, 2019

Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the…
Leukemia Treatment Could Be Bolstered By 2-in-1 Cell Combo

October 30, 2018

Led by UCLA bioengineer, researchers design delivery system to guide drugs directly to cancer cells ‘hiding’ in bone…
Key difference in how stem cells act when stressed versus when at rest revealed

August 10, 2018

Researchers from the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Jonsson Comprehensive Cancer…
Retracing a Blood Cell’s Fate

January 23, 2018

Hematopoietic stem cells (HSCs) have long been regarded as the granddaddy of all blood cells. After we are…
Bone Marrow Transplant Stem Cells Can ‘Swim’ Upstream

January 4, 2018

When a cancer patient receives a bone marrow transplant, time is of the essence. Healthy stem cells, which…
Scientists wage fight against aging bone marrow stem cell niche

March 3, 2017

Study suggests restoring body’s blood factory to boost immunity, fend off cancers As people get older so do…
Genetic factors control regenerative properties of blood-forming stem cells

December 5, 2016

Researchers from the UCLA Department of Medicine, Division of Hematology Oncology and the Eli and Edythe Broad Center…
Stem cells also rust

October 27, 2016

Oxygen in the air is well known to cause damaging rust on cars through a process known as…
Making Bone Marrow Transplants Safer

June 7, 2016

Using antibodies in place of radiation and chemotherapy Harvard Stem Cell Institute (HSCI) scientists have taken the first…
Stem cells regulate their own proliferation and their microenvironment

January 8, 2016

CNIC researchers have identified a new mechanism through which blood stem cells control their own proliferation and the…
Blood stem cell self-renewal dependent on surroundings

November 5, 2015

Blood formation: Bone marrow and blood stem cells work in close harmony Stem cells have two important capabilities:…
Scientists create a new simple method to create stem cells

October 27, 2015

Many new innovative therapies that scientists come up with rely on stem cells, especially when immune therapy and…
Scientists see through bones to uncover new details about blood-forming stem cells

September 27, 2015

A team of scientists at the Children’s Research Institute at UT Southwestern (CRI) has become the first to…
Blood stem cells in a rush — velocity determines quality

July 13, 2015

Acceleration of the G1 phase transit during cell division makes human blood stem cells more powerful For the…
Enzyme that keeps blood stem cells functional discovered

March 25, 2015

Scientists at The Scripps Research Institute discovered enzyme that is responsible for keeping blood stem cells functional to…
Even at a molecular level, taking it slow helps us cope with stress

March 19, 2015

Scientists at the University of California, Berkeley, have identified a new molecular pathway critical to aging, and confirmed…
Real-time, live assessment of blood formation

February 24, 2015

In the bone marrow, blood stem cells give rise to a large variety of mature blood cells via…
New insight that ‘mega’ cells control the growth of blood-producing cells

October 19, 2014

While megakaryocytes are best known for producing platelets that heal wounds, these “mega” cells found in bone marrow…
A Changing View of Bone Marrow Cells

February 21, 2014

In the battle against infection, immune cells are the body’s offense and defense—some cells go on the attack…
Discovery of unexpected hematopoietic differentiation pathway

September 3, 2013

The hematopoietic system that produces blood is maintained all through life by hematopoietic stem cells (HSCs). Hierarchical relationships…
Keeping Stem Cells Strong

June 10, 2013

When infections occur in the body, stem cells in the blood often jump into action by multiplying and…
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