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‘Living Fossil’ May Upend Basic Tenet of Evolutionary Theory

Yesterday

The field of evolutionary biology has seen its share of spirited debates. But if there’s one principle that…
Genome editing at the crossroads of scandal and cure

2 days ago

Genetic modification of babies in China one year ago was universally condemned. At the same time, CRISPR treatments…
Water lily of the species Nymphaea colorata. The newly reported genome sequence of the water lily sheds light on the early evolution of angiosperms, the group of all flowering plants. Image credit: Liangsheng Zhang/Penn State
Water lily genome expands picture of the early evolution of flowering plants

January 8, 2020

The newly reported genome sequence of a water lily sheds light on the early evolution of angiosperms, the…
Detailed genetic study provides most comprehensive map of risk to date for breast cancer

January 7, 2020

A major international study of the genetics of breast cancer has identified more than 350 DNA ‘errors’ that…
Human Embryonic Stem Cells (hESCs). Image credit: Nissim Benvenisty via Wikimedia, CC BY 2.5
Scientists discover molecular ‘lock’ that prevents genetic mistakes when cells divide

December 31, 2019

Research from Queen Mary University of London has provided new insight into how dividing cells control the separation…
Nanopores can identify the amino acids in proteins, the first step to sequencing

December 30, 2019

While DNA sequencing is a useful tool for determining what’s going on in a cell or a person’s…
For CRISPR, tweaking DNA fragments before inserting yields highest efficiency rates yet

December 24, 2019

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9…
Measuring Mutations in Sperm May Reveal Risk for Autism in Future Children

December 24, 2019

Spontaneous mutations in paternal sperm are linked to autism spectrum disorder; researchers have developed way to quantify those…
Grain traits traced to ‘dark matter’ of rice genome

December 19, 2019

Domesticated rice has fatter seed grains with higher starch content than its wild rice relatives — the result…
‘Conductor’ Gene Found in Plant Root Stem Cell ‘Orchestra’

December 17, 2019

In a new paper, researchers at North Carolina State University lift the veil on the “conductor” plant root…
Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection

December 11, 2019

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Due to this…
A new way to regulate gene expression

December 10, 2019

Sometimes, unexpected research results are simply due to experimental error. Other times, it’s the opposite — the scientists…
Machine Learning Provides New Paradigm in Understanding Microbial Gene Regulation

December 4, 2019

E. coli are hardy bacteria, able to live in diverse conditions from the surface of a lettuce leaf…
Researchers identify new gene mutation in familial thyroid cancers

December 2, 2019

Researchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid…
Study tracks genomic changes that reinforce darter speciation

November 28, 2019

When they share habitat, orangethroat and rainbow darters tend to avoid one another, even though they are closely…
Confocal micrograph of a young leaf of Cardamine hirsuta (hairy bittercress) with emerging leaflets, showing distribution of the RCO protein. Cell outlines are shown in gray. RCO shown here in red colour is active at the base of initiating leaflets where it reduces growth, leading to the formation of leaflets that are separated from each other. Credit: Neha Bhatia and Peter Huijser/MPG
Self-restrained genes enable evolutionary novelty

November 27, 2019

Changes in the genes that control development can potentially make large contributions to evolution by generating new morphologies…
Tracking inheritance of human mitochondrial DNA

November 27, 2019

New insight into how genetic information stored in human mitochondria is passed from one generation to the next…
Vicious Circles: Ring-shaped DNA Provides Cancer Cells with a Malignant Twist

November 27, 2019

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape. Building upon…
Genetic Variation in Individual Brain Cell Types May Predict Disease Risk

November 23, 2019

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA…
Study reveals ‘hyperhotspots’ for identifying skin cancer risk

November 14, 2019

New research by Yale University scientists reports the discovery of “hyperhotspots” in the human genome, locations that are…
Personalized gene networks may enhance study of disease

November 12, 2019

Researchers at Penn State College of Medicine have developed a new method to model how genes interact with each other…
From plants, UVA extracts a better way to determine what our genes do

November 12, 2019

Scientists at the University of Virginia School of Medicine have developed a better way to determine what our…
Genetic diversity facilitates cancer therapy

November 11, 2019

The constant battle against infectious pathogens has had a decisive influence on the human immune system over the…
Hard to Study Mutations Implicated in the Expression of Genes Associated with Schizophrenia and More

November 11, 2019

Hard-to-study mutations in the human genome, called short tandem repeats, known as STRs or microsatellites, are implicated in…
New clinical guide for the genomic diagnosis of Myelodysplastic Syndromes and Chronic myelomonocytic leukaemia

November 4, 2019

A collective work between researchers from 8 research centres and hospitals in Spain, coordinated by Francesc Solé of…
Pediatric cancer study shows usefulness of gene expression analysis

October 30, 2019

Analyzing gene expression in tumor cells from children with cancer is more likely to reveal targets for therapy…
Genetic variants for autism linked to higher rates of self-harm and childhood maltreatment

October 29, 2019

People with a higher genetic likelihood of autism are more likely to report higher childhood maltreatment, self-harm and…
Scientists pioneer new way of finding cancer-causing germs

October 24, 2019

Scientists at the University of East Anglia are pioneering a new way of finding the bacteria and viruses…
NIH funds new All of Us Research Program genome center to test advanced sequencing tools

October 22, 2019

The All of Us Research Program has selected the HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, to evaluate the use of…
Scientists unwind mystery behind DNA replication

October 21, 2019

The molecules of life are twisted. But how those familiar strands in DNA’s double helix manage to replicate…
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