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Drug reverses signs of liver disease in people living with HIV

October 16, 2019

Researchers at the National Institutes of Health and their colleagues at Massachusetts General Hospital (MGH) in Boston report…
Epigenetic Changes to Gene Affect Key Cells Behind Idiopathic Pulmonary Fibrosis

October 11, 2019

The lung stiffness and scarring characteristic of this rare disease may be linked to environmental gene alterations. In…
CAR T-Cell Therapy May Be Harnessed to Treat Heart Disease

September 12, 2019

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients’ own cells to treat certain types of…
Scleroderma Support: Patients Find Help Online

June 28, 2019

Scleroderma is a rare autoimmune disease, affecting about 300,000 Americans, but for those it affects it can be challenging to…
Special fibroblasts help pancreatic cancer cells evade immune detection

June 19, 2019

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the world. Mostly chemoresistant, PDAC so…
Unresolved Injury, Not Fibrosis, Contributes to Cisplatin-Induced CKD, Yale Study Finds

March 28, 2019

Yale School of Medicine researchers have found that the progression of acute kidney injury to chronic kidney disease…
A Step Toward Better Treatments for Fibrosis

March 1, 2019

UA researchers have developed a technology that could improve therapeutic strategies for fibrotic disorders, a leading cause of…
Inhibiting Cancer-Causing Protein Could Prevent Scleroderma Fibrosis

February 20, 2019

A protein known to play a role in cancer may also be increasing fibrosis in scleroderma patients. Scleroderma,…
New possible target for treating major common diseases

December 5, 2018

There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a…
Diabetes in Bay Area Chinese Population Linked to Fat Fibrosis

August 9, 2018

A new UC San Francisco study has discovered a key biological difference in how people of European and Chinese…
Why internal scars won’t stop growing

July 23, 2018

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But…
Devastating disease of the lung is a new research gift’s focus

July 18, 2018

The lungs are made up of some 30 to 40 different types of cells. “When you get sick,…
Study tracks therapy to slow idiopathic pulmonary fibrosis

February 12, 2018

Investigators in the Division of Allergy, Pulmonary and Critical Care have launched a pilot study to see if…
An Overlooked Cell Provides Clues About Lung Fibrosis

February 1, 2018

The cause of idiopathic pulmonary fibrosis (IPF) is unknown, but a discovery from the lab of Anjelica Gonzalez…
MAGNET Study Sees Potential for MRE in Measuring Liver Fibrosis in Children

May 13, 2017

Researchers at University of California San Diego School of Medicine, with collaborators across the nation, have determined that…
Study points a way to better implants

March 21, 2017

Medical devices implanted in the body for drug delivery, sensing, or tissue regeneration usually come under fire from…
Hormone identified that limits liver fibrosis

October 15, 2016

Potential applications for treating nonalcoholic steatohepatitis, cirrhosis Nonalcoholic steatohepatitis (NASH) has been emerging worldwide and effective treatment, especially…
Technique May Identify Patients with Fast-Progressing Fibrosis in Nonalcoholic Fatty Liver Disease

October 13, 2016

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method…
Circulating immune cells as biomarkers for idiopathic pulmonary fibrosis

September 2, 2016

Researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), have discovered that…
Study shows that Wnt secretion preventing drugs may reduce renal fibrosis

March 31, 2016

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease…
Fighting liver fibrosis, the wound that never heals

December 8, 2015

Salk team develops drug that prevents and reverses deadly liver damage in mice Chronic damage to the liver…
Researchers Develop Scar-like Culture Systems to Understand and Treat Fibrosis

July 16, 2015

A scar might be a reminder of an accident or surgery, but the fibrous tissue that makes up…
Scientists discover treatment to two fatal lung diseases

June 16, 2015

Researchers at the University of Georgia have found a potential drug treatment for two fatal lung diseases. Pulmonary…
Promising new target may treat pulmonary fibrosis

March 20, 2015

By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research…
Identifying the cellular origin of fibrosis

December 3, 2014

Researchers from Brigham and Women’s Hospital (BWH) have identified what they believe to be the cells responsible for…
Is a ‘buttery’ molecule behind cystic fibrosis flare-ups?

February 24, 2014

Katrine Whiteson and colleagues identified a lung-damaging molecule in higher concentrations in cystic fibrosis patients during symptom flare-ups.…
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