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Genome editing at the crossroads of scandal and cure

6 days ago

Genetic modification of babies in China one year ago was universally condemned. At the same time, CRISPR treatments…
A Simple Twist of Cell Fate

January 15, 2020

How do a couple of universally expressed proteins in stem cells and developing embryos influence an individual cell’s…
Backbone of Success: Segmentation Clock Inside our Cells

January 9, 2020

More than 20 years ago, the lab of developmental biologist Olivier Pourquié discovered a sort of cellular clock in chicken…
Graduate student researcher hits the lights on cells’ development

December 9, 2019

Combining light and a protein linked to cancer, researchers at Princeton University have created a biological switch to…
Human Embryonic Stem Cells (hESCs). Image credit: Nissim Benvenisty via Wikimedia, CC BY 2.5
Animal embryos evolved before animals

November 28, 2019

A new study by an international team of researchers, led by scientists from the University of Bristol and…
How Stem Cells Make Decisions

October 23, 2019

Pluripotency is a feature of stem cell populations in which individual cells must know a great deal about…
Ventricles in the embryonic mouse heart. Cardiac muscle cells are labeled in green; the muscle cells derived from neural crest cells are labeled in magenta. Image credit: Bronner laboratory
Mending Broken Hearts with Neural Crest Cells

October 23, 2019

Zebrafish—striped fish a few centimeters long—have the ability to regrow up to 20 percent of their hearts after…
Micropatterned plates contain multiple colonies of embryonic cells. The plates developed at Rice allow researchers to view and manipulate the colonies as they grow to determine how signaling pathways help cells differentiate. Illustration by Jeff Fitlow/Rice University
Embryo’s early development revealed in a dish

October 21, 2019

During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet…
Yale researchers develop way to help brain organoids thrive

October 8, 2019

Brain organoids created from human embryonic stem cells offer scientists a powerful way to study the developing brain…
New study answers longstanding cell-development riddle

September 10, 2019

During the lifetime of a body – whether human, fish or any other type of vertebrate – cells…
Undercover Evolution

September 6, 2019

Providing a glimpse of the hidden workings of evolution, a group of researchers at UC Santa Barbara have…
Researchers wirelessly hack ‘boss’ gene, a step toward reprogramming the human genome

July 17, 2019

It seems like everything is going wireless these days. That now includes efforts to reprogram the human genome.…
Awakening of the zygote genome over time as decreasing individual cell size triggers early embryo transcription. Image credit: Hui Chen, Penn Medicine; Cell Press
Size Matters: New Data Reveals Cell Size Sparks Genome Awakening in Embryos

July 3, 2019

Transitions are a hallmark of life. When dormant plants flower in the spring or when a young adult…
New study challenges claim that exogenous RNA is essential for sperm function

July 3, 2019

Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which…
Replicating Fetal Bone Growth Process Could Help Heal Large Bone Defects

June 7, 2019

To treat large gaps in long bones, like the femur, which result from bone tumor removal or a…
Remembrance of Things Past

March 25, 2019

In research that casts cells as curators of their own history, Harvard Medical School researchers at Dana-Farber Cancer…
Speed limit on DNA-making sets pace for life’s first steps

March 20, 2019

Scientists puzzled for two decades over this seemingly unnecessary withholding. Now researchers at Princeton University have shown that…
Embryos’ signals take multiple paths

March 12, 2019

Rice University scientists have found significant differences between the methods signaling pathways use to prompt cells to differentiate…
Embryos’ signaling proteins go with the flow

March 4, 2019

Rice University scientists say context rules dynamic mechanisms that turn cells into tissues. How cells in developing embryos…
How the fruit fly got its stripes: Researchers explore the precision of embryonic development

February 4, 2019

In a new study published in the journal Cell, the team showed that cells determine exactly where they need to…
Human Embryonic Stem Cells (hESCs). Image credit: Nissim Benvenisty via Wikimedia, CC BY 2.5
Discovery in cell development changes understanding of how genes shape early embryos

January 10, 2019

Our bodies hold roughly 14 trillion cells, each containing a nucleus with DNA measuring two meters long by…
A better look at how cells move

December 12, 2018

A new computational model clarifies the structure and mechanics of soft, shape-changing cells, potentially giving scientists a better…
Researchers discover a new gear in life’s clock: Vitamin D

November 23, 2018

New research from Portland State University finds vitamin D, or a lack thereof can trigger or suspend embryonic development…
Discovery of a new gene could shed light on chemical exposure effects in humans

November 21, 2018

The discovery of a new gene in zebrafish could lead to a better understanding of how exposure to…
Embryos remember the chemicals that they encounter

November 13, 2018

We all start out as a clump of identical cells. As these cells divide and multiply, they gradually…
Careful — You Are Made of ‘Glass’

September 10, 2018

Ever wondered how groups of cells managed to build your tissues and organs while you were just an…
Unexpected outcomes sound warning for treatment of genetic diseases using gene editing in embryos

August 17, 2018

New research led by the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide…
Research shows cannabis has detrimental effects on developing fish embryos

July 17, 2018

Exposure to the main chemical components of cannabis has a detrimental effects on developing zebrafish embryos, according to…
Revealing the mysteries of early development

May 28, 2018

Zebrafish embryos are transparent and develop outside the mother’s body, enabling scientists to get a detailed view of…
Stem cell symposium to highlight clinical trials, safety and regulation

April 19, 2018

Twenty years ago this fall, a team of scientists led by James Thomson at the University of Wisconsin–Madison…
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