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Hormone resistance in breast cancer linked to DNA ‘rewiring’

Yesterday

Garvan researchers have revealed changes to the 3D arrangement of DNA linked to treatment resistance in ER+ breast…
New Mechanisms Describe How the Genome Regulates Itself

2 days ago

An organism’s genome contains all of the information necessary for each of its cells and tissues to develop…
Analyzing DNA in soil could be an effective way of tracking animals

2 days ago

It’s hard to protect something you can’t find. A new Stanford study reveals sampling soil for animals’ left-behind…
Snake-like proteins can wrangle DNA

5 days ago

It turns out the coiled snakes often used to symbolize medical knowledge are more than apt. They also mimic a…
Water lily of the species Nymphaea colorata. The newly reported genome sequence of the water lily sheds light on the early evolution of angiosperms, the group of all flowering plants. Image credit: Liangsheng Zhang/Penn State
Water lily genome expands picture of the early evolution of flowering plants

January 8, 2020

The newly reported genome sequence of a water lily sheds light on the early evolution of angiosperms, the…
Study shines light on how DNA keeps its 3D shape

January 8, 2020

A protein that maintains DNA’s 3D arrangement may be central to the health of human cells. Just as…
Mutant proteins linked to DNA damage, muscular dystrophy

December 31, 2019

New Cornell-led research has found a strong connection between DNA damage triggered by mutations in proteins that surround the…
For CRISPR, tweaking DNA fragments before inserting yields highest efficiency rates yet

December 24, 2019

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9…
Understanding what makes black pigment black

December 19, 2019

Scientists have for the first time “unmixed” the black pigment that colors our skin and gives bananas their…
‘DNA is not your destiny’: Genetics a poor predictor of risk for most diseases, study suggests

December 19, 2019

Diseases including many cancers, diabetes and Alzheimer’s have a genetic contribution of five to 10 per cent at…
Researchers Uncover Defective Sperm Epigenome that Leads to Male Infertility

December 19, 2019

Male Infertility New mouse model allows researchers to track defective sperm and potentially find ways to correct it.…
Origin story: Rewriting human history through our DNA

December 19, 2019

For most of our evolutionary history — for most of the time anatomically modern humans have been on…
Screen could offer better safety tests for new chemicals

December 17, 2019

It’s estimated that there are approximately 80,000 industrial chemicals currently in use, in products such as clothing, cleaning…
New tool predicts three-dimensional organization of human chromosomes

December 11, 2019

University of Wisconsin–Madison researchers have developed a computational tool that can accurately predict the three-dimensional interactions between regions…
A new way to regulate gene expression

December 10, 2019

Sometimes, unexpected research results are simply due to experimental error. Other times, it’s the opposite — the scientists…
CRISPR-Resistant Viruses Build ‘Safe Rooms’ to Shield Genomes from DNA-Dicing Enzymes

December 10, 2019

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life…
Researchers identify gene behind spread of deadly breast cancer

December 10, 2019

If your DNA is a cookbook, a single gene is a recipe. But it’s a flexible recipe that…
Storing data in everyday objects

December 10, 2019

A research team with members from ETH Zurich has discovered a new method for turning nearly any object…
Structurally designed ‘DNA star’ creates ultrasensitive test for dengue virus

November 28, 2019

By folding snippets of DNA into the shape of a five-pointed star using structural DNA nanotechnology, researchers have…
Confocal micrograph of a young leaf of Cardamine hirsuta (hairy bittercress) with emerging leaflets, showing distribution of the RCO protein. Cell outlines are shown in gray. RCO shown here in red colour is active at the base of initiating leaflets where it reduces growth, leading to the formation of leaflets that are separated from each other. Credit: Neha Bhatia and Peter Huijser/MPG
Self-restrained genes enable evolutionary novelty

November 27, 2019

Changes in the genes that control development can potentially make large contributions to evolution by generating new morphologies…
Tracking inheritance of human mitochondrial DNA

November 27, 2019

New insight into how genetic information stored in human mitochondria is passed from one generation to the next…
Vicious Circles: Ring-shaped DNA Provides Cancer Cells with a Malignant Twist

November 27, 2019

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape. Building upon…
Genetic Variation in Individual Brain Cell Types May Predict Disease Risk

November 23, 2019

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA…
Non-coding DNA located outside chromosomes may help drive glioblastoma

November 22, 2019

Extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going—elements that could represent new drug…
Scientists Detect Sugars in Meteorites, Providing Clues to the Origin of Life

November 20, 2019

The hypothesis that meteorite bombardment of prehistoric Earth might have kick-started the development of biological life on the…
Visualizing DNA Labels in Cells and Tissues

November 20, 2019

Complex living things are made up of collections of individual cells all working together. Understanding how these assemblages…
Mitochondrial Mixing Mechanism Critical for Sperm Production in Mice

November 19, 2019

Mitochondria, often thought of as the powerhouses of cells, are just one part of a larger living thing,…
Chemists map an artificial molecular self-assembly pathway with complexities of life

November 15, 2019

Two pathways diverged in chemical synthesis, and one molecule took them both. Chemists at the University of Tokyo…
CRISPR: More than just for gene editing?

November 13, 2019

The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia…
Personalized gene networks may enhance study of disease

November 12, 2019

Researchers at Penn State College of Medicine have developed a new method to model how genes interact with each other…
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