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Speeding Up Treatments for ALS

February 6, 2020

Therapeutic solutions for amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease) could be on the horizon thanks to…
Injection of Virus-Delivered Gene Silencer Blocks ALS Degeneration, Saves Motor Function

December 24, 2019

Novel spinal therapy/delivery approach prevented disease onset in neurodegenerative ALS disease model in adult mice and blocked progression…
New clues to the link between ALS and type 2 diabetes

December 10, 2019

Patients with ALS (amyotrophic lateral sclerosis) often suffer from type 2 diabetes. This phenomenon has since long remained…
Seeking better treatment for ALS, Lou Gehrig’s disease

November 4, 2019

There is currently no cure for amyotrophic lateral sclerosis (ALS). But new research could open up avenues for…
New research center to explore muscle health and disease

October 15, 2019

A new, interdisciplinary muscle research center is celebrating its opening at its main location at UW Medicine South…
Research suggests how environmental toxin produced by algae may lead to ALS

September 17, 2019

Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to…
New ALS biomarkers, potential new drug targets described by researchers

July 16, 2019

Amyotrophic lateral sclerosis, or ALS, is an adult-onset neurodegenerative disease that causes paralysis and ultimately death when the…
Freeze frame: researches solve how cells unfold proteins

July 8, 2019

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear…
Protein Clumps in ALS Neurons Provide Potential Target for New Therapies

July 3, 2019

Amyotrophic lateral sclerosis (ALS) is a neurological condition that affects motor neurons — the nerve cells that control…
Copper compound shows further potential as therapy for slowing ALS

July 3, 2019

A compound with potential as a treatment for ALS has gained further promise in a new study that…
Stem cells provide information about neuron resilience in ALS

May 13, 2019

Researchers at Karolinska Institutet in Sweden have developed a stem cell based model in order to study the…
A New Clue in the Mystery of ALS, Frontotemporal Dementia

April 25, 2019

A special focus on rogue proteins may hold future promise in stopping the progression of nerve cell destruction…
Pesticide Exposure Contributes to Faster ALS Progression

March 1, 2019

A new study helps determine the role of pesticides and pollutants during the course of the progressive neurodegenerative…
Can a nerve injury trigger ALS?

February 21, 2019

A growing collection of anecdotal stories raises the possibility that nerve injury in an arm or a leg…
Statins could protect against motor neurone disease

February 15, 2019

High cholesterol has been found to be a possible risk factor for the development of motor neurone disease…
New method for studying ALS more effectively

December 13, 2018

The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose…
Testing new drugs with “ALS-on-a-chip”

October 11, 2018

There is no cure for amyotrophic lateral sclerosis (ALS), a disease that gradually kills off the motor neurons…
Finding that links ALS/ATAXIA to cellular stress opens

September 20, 2018

Few treatments exist for neurodegenerative diseases that progressively rob a person’s ability to move and think, yet the…
Drugs in development for cancer may also fight brain diseases, including ALS

August 14, 2018

A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including…
New Funding to Significantly Boost Cancer, ALS Research

June 25, 2018

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has…
Changes to Specific MicroRNA Involved in Development of Lou Gehrig’s Disease

May 28, 2018

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or…
New clues may help improve speech for people with ALS

May 28, 2018

New clues may help improve speech for people with dysarthria, a type of speech disorder commonly found in…
Biologists discover function of gene linked to familial ALS

May 7, 2018

MIT biologists have discovered a function of a gene that is believed to account for up to 40…
ALS, rare dementia share genetic link

April 17, 2018

Nearly half of all patients with amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder, develop cognitive problems that…
UCSF Researcher Identifies Risk Genes for ALS

April 16, 2018

The largest analysis to date of genetic data in amyotrophic lateral sclerosis (ALS) – the muscle-crippling neurodegenerative disease…
Better understanding ALS by looking at how cells change

March 30, 2018

It took eight long years of research, but now an international team led by neuroscientists at Université de…
NIH-supported international team confirms new genetic mutation link to ALS

March 27, 2018

Kinesin family member 5A (KIF5A), a gene previously linked to two rare neurodegenerative disorders, has been definitively connected…
Focus on early stage of illness may be key to treating ALS, study suggests

March 22, 2018

A new kind of genetically engineered mouse and an innovation in how to monitor those mice during research…
Why nerve cells die in ALS and some dementia cases

February 6, 2018

A new USC Stem Cell study, published in Nature Medicine, describes how a gene mutation led to toxicity in nerve…
Research reveals atomic-level changes in ALS-linked protein

January 19, 2018

For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral…
New study may lead to changes in treatment of ALS patients

December 18, 2017

A Penn State study brings researchers one step closer to better understanding and treating dysarthria, a type of…
UA Researchers Pinpoint Pathway to Muscle Paralysis

December 5, 2017

Researchers at the University of Arizona have taken an essential step forward in the quest to find the…
Investigating protein associated with ALS points to possible targets for therapeutic intervention

December 4, 2017

Scientists at the University of Alberta may have found possible targets for therapeutic interventions in the fight against…
A promising new medication for ‘Lou Gehrig’s disease’

November 20, 2017

Researchers from the University of Montreal Hospital Research Centre (CRCHUM) and the Cumming School of Medicine (CSM) at…
Turning to religion helps dying people to find meaningfulness in life

August 18, 2017

Dying is extremely mystified phenomenon in our world. We are scared of dying and we would do anything…
New therapeutic approach for ALS

July 26, 2017

A group of University of Tokyo researchers and their collaborators have shown that enlarging the neuromuscular junctions of…
Study highlights role of rare genetic mutations in ALS

June 29, 2017

Ninety to 95 percent of amyotrophic lateral sclerosis (ALS) cases are “sporadic,” meaning these patients had no clear…
Biomarker Test for Lou Gehrig’s Disease Useful in Diagnosing Canine Neurodegenerative Disease

May 4, 2017

In 2009, Joan Coates, a veterinary neurologist, along with other researchers at the University of Missouri and the…
Scientists discover urinary biomarker that may help track ALS

March 24, 2017

A study in Neurology suggests that analyzing levels of the protein p75ECD in urine samples from people with…
Brain-controlled robot will help patients with severe muscle paralysis due to amyotrophic lateral sclerosis

January 17, 2017

In a new research project, signals from the brain are decoded by a computer and used to control…
Collapse of mitochondria-associated membrane in ALS

November 10, 2016

Amyotrophic lateral sclerosis (ALS) is an adult onset, fetal neurodegenerative disease that selectively affects motor neurons. To date,…
An Agent of Demise

August 27, 2016

Scientists from Harvard Medical School have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis,…
New areas of the brain identified where ALS-implicated gene is active

August 2, 2016

For the first time novel expression sites in the brain have been identified for a gene which is…
New areas of the brain identified where ALS gene is active

August 2, 2016

University of Bath scientists identify 2 regions of mouse brains where C9orf72 is expressed For the first time…
Finding a treatment for ALS

July 14, 2016

University of Tokyo researchers have shown that a new drug used to treat epilepsy may hold the key…
Stem cell treatment for Lou Gehrig’s disease may be safe

June 30, 2016

A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, suggests that…
Aggregated protein in nerve cells can cause ALS

May 9, 2016

Persons with the serious disorder ALS, can have a genetic mutation that causes the protein SOD1 to aggregate…
Targeting upper motor neurons to treat ALS

February 2, 2016

Selective gene delivery modifies diseased cells Scientists have demonstrated for the first time that it is possible to…
New therapy halts progression of Lou Gehrig’s disease in mice

January 29, 2016

Researchers at Oregon State University announced that they have essentially stopped the progression of amyotrophic lateral sclerosis (ALS),…
Nuclear transport problems linked to ALS and FTD

October 19, 2015

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to…
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