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Corteva AgriscienceTM Challenge: Seeking Natural Products or Natural Product-Derived Small Molecules

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Posted June 19, 2019

The Competitor is seeking pure natural products and semi-synthetic natural products for pest control. Material supply of compounds which are natural products or natural-product derived small molecules is desired. Crude extracts and mixtures are not requested for this Challenge.

Vegetables and fruits. Image credit: Gpics/Wikipedia/CC BY-SA 3.0

Overview

The discovery of novel modes of action for use in crop protection remains an ongoing challenge for multiple reasons, including the increasing demand for higher protein diets, evolution of resistance to existing solutions, and regulatory and societal pressures to continually improve the safety and toxicological profiles of crop protection chemicals.

Because bacteria, plants, insects and fungi are in a continual evolutionary and ecological battle in the environment, each species develops its own methods for survival.  Some of these tools include the production of small molecules that are generated for a very specific purpose.  As farmers seek to find new crop protection solutions to reduce fungal, insect and weed impact on crop yields, there is an opportunity to explore the use of these small molecules developed by nature to improve agriculture.

As the leader in Natural Products Discovery, Corteva AgriscienceTM has historically discovered and developed a number of natural products and semi-synthetic natural products for pest control.  However, this discovery process of molecules with novel modes of action is an ongoing challenge in the agricultural industry, and as such we are seeking input from the broader scientific community to gain access to more chemical space; in particular, the biologically relevant space that natural products are known to occupy.

Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on August 12, 2019.

Source: InnoCentive

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