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NCATS ASPIRE Design Challenge 1: Integrated Chemistry Database for Translational Innovation in Pain, Opioid Use Disorder and Overdose

Posted December 28, 2018

Challenge 1 aims to address the need for an open-source, controlled-access database that incorporates all currently available chemical, biological and clinical data of known opioid and non-opioid based analgesics, drugs of abuse and drugs used to treat drug abuse.

Image credit: NIH

This Challenge requires submission of only a detailed description of the design of a database, not the final working database. In order to serve the purpose of the NCATS ASPIRE Program, the database should be highly disease-specific (focusing only on opioid- and non-opioid-based analgesics, drugs of abuse and drugs used to treat drug abuse) but able to be adapted for scalability and/or use for other disorders. Data and data management systems could be accessed and utilized using an application programming interface (API).

The database should offer effective visualizations through a built-in graphical user interface (GUI) representing an analytics dashboard and/or an external porting mechanism to other visualization tools, and it should offer functionality that facilitates data use in training and validating advanced machine learning algorithms or applications developed in Challenge 3.

Source: NIH

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