Challenge 1 aims to address the need for an open-source, controlled-access database that incorporates all currently available chemical, biological and clinical data of known opioid and non-opioid based analgesics, drugs of abuse and drugs used to treat drug abuse.
This Challenge requires submission of only a detailed description of the design of a database, not the final working database. In order to serve the purpose of the NCATS ASPIRE Program, the database should be highly disease-specific (focusing only on opioid- and non-opioid-based analgesics, drugs of abuse and drugs used to treat drug abuse) but able to be adapted for scalability and/or use for other disorders. Data and data management systems could be accessed and utilized using an application programming interface (API).
The database should offer effective visualizations through a built-in graphical user interface (GUI) representing an analytics dashboard and/or an external porting mechanism to other visualization tools, and it should offer functionality that facilitates data use in training and validating advanced machine learning algorithms or applications developed in Challenge 3.