Google Play icon

Research measures potentially damaging free radicals in cigarette smoke

Share
Posted March 30, 2017

Smoking cigarettes can lead to illness and death. Free radicals, which are atoms or groups of atoms with unpaired electrons, in inhaled smoke are thought to be partly responsible for making smokers sick. Now researchers from Penn State College of Medicine and College of Agricultural Sciences report a method for measuring free radicals in cigarette smoke that could help improve our understanding of the relationship between these substances and health.

Cigarette. Credit: Free Dough via Flickr, CC BY 2.0

John Richie, professor of public health sciences and pharmacology is lead investigator. The study, “Variation in Free Radical Yields from U.S. Marketed Cigarettes” appears in the American Chemical Society’s (ACS) journal, Chemical Research in Toxicology.

Cigarette smoking is the leading preventable cause of death in the U.S., according to the Centers for Disease Control and Prevention. Understanding why is a challenge, given that cigarette smoke is a complex mixture of more than 7,000 compounds. Much of the blame has been placed on the 93 cigarette-related carcinogens and toxins on the U.S. Food and Drug Administration’s list of hazardous and potentially hazardous chemicals. But previous studies have reported that risk assessments based on these compounds underestimate the actual number of illnesses caused by smoking. Accounting for free radicals, which are known to cause oxidative damage in the body, could help fill that gap. But they are not listed on the FDA’s list and are difficult to study because they don’t stick around for long. So Richie and colleagues wanted to find a reliable way to measure free radicals in cigarette smoke.

The researchers developed a standardized protocol for measuring free radicals in smoke first by using a control cigarette and a technique called electron paramagnetic resonance spectrometry. They then applied the same protocol to 27 varieties of commercial cigarettes. The study found that the levels of gas-phase radicals ranged widely across the varieties while particulate-phase radicals showed less variability. An analysis of potential factors accounting for the differences found that highly ventilated cigarettes tended to produce lower levels of both gas- and particulate-phase free radicals. The researchers say their method could be used to assess people’s exposure to free radicals and help determine potential health effects.

Source: Penn State University

Featured news from related categories:

Technology Org App
Google Play icon
85,387 science & technology articles

Most Popular Articles

  1. New treatment may reverse celiac disease (October 22, 2019)
  2. "Helical Engine" Proposed by NASA Engineer could Reach 99% the Speed of Light. But could it, really? (October 17, 2019)
  3. New Class of Painkillers Offers all the Benefits of Opioids, Minus the Side Effects and Addictiveness (October 16, 2019)
  4. The World's Energy Storage Powerhouse (November 1, 2019)
  5. Plastic waste may be headed for the microwave (October 18, 2019)

Follow us

Facebook   Twitter   Pinterest   Tumblr   RSS   Newsletter via Email