Researchers from the Department of Pharmacy & Pharmacology used a technique called stimulated Raman scattering microscopy to build up a detailed picture of how three commonly used solvents penetrate the nail over time.
Published in the Proceedings of the National Academy of Science, USA (PNAS), the work was undertaken by researchers in the group of Professor Richard Guy and involved close collaboration with a number of colleagues.
Professor Guy said: “I’m absolutely delighted that this paper, first authored by my postdoctoral research associate Wing Sin Chiu, has been published in PNAS, one of the world’s most-cited and comprehensive multidisciplinary scientific journals.
“The article was co-authored by Bath colleagues, Natalie Belsey and Begoña Delgado-Charro, and by Julian Moger and Natalie Garrett at the University of Exeter, one of our GW4 partners.”
Nail diseases are hard to treat because enabling drugs to penetrate the compact honeycomb-like structure of the nail (pictured right) is particularly difficult. This research could help improve how medicines to treat nail disease are made.
Source: University of Bath