In a study published online by Applied Physics Letters, a multidisciplinary team led by Physics Professor Otto Zhou, PhD; Radiation Oncology Associate Professor X. Sha Chang, PhD; and Physics Professor Jianping Lu, PhD, built a device using carbon nanotube-based x-ray source array technology developed at UNC that can generate microbeam radiation with similar characteristics as the beams generated by synchrotron radiation. Researchers from Applied Sciences and Radiology at UNC also participated in this study.
Zhou, a member of the UNC Lineberger Comprehensive Cancer Center, points to several studies that have shown that microbeam radiation destroyed tumors and increased survival by as much as a factor of ten in brain tumor bearing animals treated with the technique. While the potential of the technology has been proven, the massive infrastructure needed to undertake the studies has prevented research from being researched for clinical use.
“The innovation here, what we have done at the university, is to build equipment that is compact and can be potentially used in a hospital and achieve similar therapeutic value. The fact that the microbeam can deliver the radiation effect is known, the experiments have been done, but the use of the synchrotron-based equipment is not practical,” said Zhou.
Read more at: Phys.org