Google Play icon

Brain regions active in anxiety and performance determined

Share
Posted June 11, 2013
This news or article is intended for readers with certain scientific or professional knowledge in the field.

Despite increasing interest in anxiety and psychological stress in daily life, little is known about neural correlates that underlie maintained psychological stress and their relationship with anxiety. In particular, the activation characteristics of lateral prefrontal subregions and their relationship with anxiety and cognitive performance under maintained psychological stress remain unknown.

Prefrontal subregions play distinct roles in mediating anxiety and performance under maintained psychological stress. © Ryu Takizawa.

Prefrontal subregions play distinct roles in mediating anxiety and performance under maintained psychological stress. © Ryu Takizawa.

Dr Ryu Takizawa and Professor Kiyoto Kasai in Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo used near-infrared spectroscopy (NIRS), a noninvasive and “real-world” functional neuroimaging method, to investigate hemodynamic responses in wide areas of the prefrontal cortex (PFC) and the influence of anxiety under conditions of maintained stress induced by a continuous arithmetic task (2 sets, 15 min each) performed in a natural sitting posture.

Although anxiety and performance are not directly correlated, the hemodynamic response in the medial portion of the lateral PFC (dorsolateral and frontopolar PFC) was significantly associated with anxiety, while hemodynamic responses in the ventrolateral PFC were associated with performance. This is the first study to suggest that PFC sub-regions play distinct roles in mediating anxiety and performance under maintained psychological stress and may lead to a better understanding of neural correlates for anxiety in everyday life.

This study was supported by grants from the Ministry of Health, Labour, and Welfare, and the “Development of biomarker candidates for social behavior” project of the Strategic Research Program for Brain Sciences sponsored by MEXT.

Source: University of Tokyo

Featured news from related categories:

Technology Org App
Google Play icon
85,387 science & technology articles

Most Popular Articles

  1. New treatment may reverse celiac disease (October 22, 2019)
  2. "Helical Engine" Proposed by NASA Engineer could Reach 99% the Speed of Light. But could it, really? (October 17, 2019)
  3. New Class of Painkillers Offers all the Benefits of Opioids, Minus the Side Effects and Addictiveness (October 16, 2019)
  4. The World's Energy Storage Powerhouse (November 1, 2019)
  5. Plastic waste may be headed for the microwave (October 18, 2019)

Follow us

Facebook   Twitter   Pinterest   Tumblr   RSS   Newsletter via Email